Which of the following factors may contraindicate weaning from mechanical ventilation?

• A. Ongoing respiratory acidosis
• B. High blood pressure
• C. Improved lung function
• D. Normal electrolyte levels

Answer: (A)

Ongoing respiratory acidosis is a critical factor that may contraindicate weaning from mechanical ventilation. This condition indicates that the patient's lungs are not adequately removing carbon dioxide from the blood, leading to an accumulation of this gas and resulting in an acidic environment in the body. When a patient is experiencing respiratory acidosis, it suggests that their respiratory system is compromised, and they may not be able to sustain adequate ventilation and oxygenation on their own.

In such a scenario, attempting to wean a patient from mechanical ventilation could result in the deterioration of their respiratory status, potentially leading to respiratory failure. Therefore, healthcare providers typically assess blood gas values, including pH and carbon dioxide levels, before considering weaning.

In contrast, high blood pressure, while it may indicate a cardiovascular issue, does not directly affect the patient's ability to breathe or their ventilation status. Improved lung function typically suggests that the patient may be ready to be weaned from mechanical ventilation, and normal electrolyte levels indicate metabolic stability, which is generally a positive sign when assessing readiness to wean.